calculate the effects of changing the dosing interval on the steady-state concentration.
Drug A has the following characteristics: Volume of distribution (Vd) = 40 liters; Half-Life = 15 hours. Assuming a dose of 150 mg given every twenty-four hours and a 70% absorption rate.
Maintaining the parameters given for Drug A, calculate the effects of changing the dose interval on the steady state concentration. Use a dose size of 300 mg and calculate the effects of using the following dose intervals: 48 hours; 24 hours; 12 hours; 6 hours.